The PKD1L1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PKD1L1. This antibody recognizes Human antigen. The PKD1L1 Antibody has been validated for the following applications: ELISA, Immunofluorescence, and Immunohistochemistry.
Description
Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning